Multi-vial Discount Available
Select Size
Research Use Only · Not for human or veterinary consumption.
People also purchased
10mg · $39.00
10mg · $42.00
10mg · $21.00
Safety Data Sheet
In the 16-section GHS format covering identification, hazards, handling, storage and disposal.
- Ships Next Day
- Quality Guaranteed
- Cold-Chain Shipping
- Free US Shipping Over $150
What is HEP-1 (Gepon)?
HEP-1 is a chain of 14 amino acids. Its sequence is copied from a short stretch of a much larger human protein called ezrin, which sits just inside the membrane of many cells and helps anchor the cell's internal scaffolding. HEP-1 is only that short piece, not the whole protein, and nothing known about the whole protein carries over to it. It is also sold in Russia under the name Gepon, and almost all the published work on it comes from the one group that developed it.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
HEP-1 (Gepon) Research & Reference
What HEP-1 (Gepon) does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
Frequently Asked Questions
Is HEP-1 (Gepon) third-party tested for purity?+−
Yes. Every batch of HEP-1 (Gepon) is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
What does "Research Use Only" mean?+−
It means HEP-1 (Gepon) is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. HEP-1 is legal to purchase in the United States for in vitro and non-clinical laboratory research. It carries no FDA approval or therapeutic indication for human use. HEP-1 is not a scheduled substance under the Controlled Substances Act. It has been registered for human use in Russia under the brand name Gepon since 2001, according to its developers. It holds no marketing authorisation in the UK, the EU or the US, and the material supplied here is a research-grade preparation rather than any registered medicine. Sold strictly for qualified research use, not human or veterinary administration.
How is HEP-1 (Gepon) shipped and stored?+−
HEP-1 (Gepon) ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
How much independent research exists on HEP-1?+−
Very little. A PubMed search on the names Gepon and Hepon returns twenty records, one of them a false match on an author's surname. The strongest positive animal and cell studies, a mouse colitis study and a mouse fibroblast study, both carry an inventor of the peptide on the author line. The human record is wider than one study: clinical reports are indexed in several different conditions, and several of them, including the largest controlled one, in 126 patients, carry neither inventor on the author line. No independent replication appears in the retrieved literature. The HEP-1 research article reports what the studies found and states this limitation alongside it.
Immune & Thymic Research
Related Compounds
>99%
>99%
>99%
99%
Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.