Buy Epithalon Research Peptide

Epithalon (CAS 307297-39-8), also known as Epitalon or Epithalone, is a synthetic tetrapeptide with the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Defined by the amino acid sequence Ala-Glu-Asp-Gly, Epithalon was synthesised based on the amino acid composition of Epithalamin, a polypeptide preparation originally derived from bovine pineal tissue. Developed at the Saint Petersburg Institute of Bioregulation and Gerontology, it belongs to a class of short synthetic peptides investigated as bioregulators in the Russian scientific literature. Produced via solid-phase peptide synthesis, Epithalon is associated with telomerase-related signaling and pineal gland neuroendocrine pathways in preclinical gerontology research.

Epithalon has been extensively investigated as a tetrapeptide bioregulator in preclinical aging research. Published in vitro studies have examined its interaction with telomerase reverse transcriptase (hTERT) expression in human somatic cell preparations, documenting Epithalon-mediated induction of telomerase activity and telomere elongation in human somatic cell preparations and characterizing the Ala-Glu-Asp-Gly tetrapeptide as a telomerase-activating signal in aging cell culture models [1]. In vivo rodent studies have investigated Epithalon in long-term aging protocols, with published research examining spontaneous tumor incidence in aged animal cohorts and documenting reduced carcinogenesis endpoints across extended observation periods in aged rodent preparations, with researchers from the Khavinson laboratory and collaborators characterizing gerontological outcomes following Epithalon administration in controlled preclinical aging models [2], making Epithalon a key reference compound in peptide bioregulator research examining telomerase-related signaling and gerontological endpoints in preclinical aging models.

Epithalon is produced to research-grade standards and independently verified by third-party HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available to view and download directly on the product page.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Martina Rossi, PhD

Scientific Contributor and Reviewer

Reviewed for scientific accuracy, 11 August 2026

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