KPV Research Peptide
KPV is three amino acids joined together: lysine, proline and valine.
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Research Use Only · Not for human or veterinary consumption.
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Certificates of Analysis
Every batch is tested by an independent laboratory before release.
Verify Batch. Lot-level COA, Batch DF/KPV/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.
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What is KPV?
KPV is three amino acids joined together: lysine, proline and valine. Its sequence matches the tail end of a larger natural peptide called alpha-MSH, the last three of its thirteen amino acids, except that alpha-MSH ends in an amide group and this version ends in a free acid. The material sold here is made in the laboratory. Research on it has centered on inflammatory signaling in the gut lining, on wound closure on the surface of the eye, and on its effect on microbes.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
KPV Research & Reference
What KPV does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
KPV Batch Results
Batch DF/KPV/062026
- Laboratory
- Kovera Labs
- Certified
- August 13, 2026
- Sample
- 10 mg vial
- Report
- KVR-2026-207A91
An independent laboratory, Kovera Labs, tested a sample from this batch. These are the results on its certificate.
Purity
Pass99.418%
RP-HPLC, C18 column, 214 nm
Identity
PassConfirmed
LC-MS
Purity is an HPLC figure: the main peak’s share of everything the detector recorded at one wavelength. It’s not a weight. What a purity figure counts →
Check it with the lab. Kovera Labs’ verification page looks a certificate up by its report number. Product, batch, date and results should match this page.
Chromatogram
RP-HPLC · C18 · DAD 214 nm
Frequently Asked Questions
Is KPV third-party tested for purity?+−
Yes. Every batch of KPV is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
Can I see the Certificate of Analysis before buying?+−
Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.
What does "Research Use Only" mean?+−
It means KPV is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. KPV is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. KPV is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is KPV shipped and stored?+−
KPV ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
Is KPV the same as alpha-MSH?+−
No. Alpha-MSH is a thirteen-amino-acid peptide. KPV has the sequence of its last three amino acids, lysine-proline-valine, on their own. Alpha-MSH is amidated at its C-terminus, so the hormone's own C-terminal fragment is the amide KPV-NH2, while this product is the free acid. Melanocortin products related to alpha-MSH are sold in a separate category here, and research on one is not research on the other.
Does KPV act on melanocortin receptors?+−
The published record is not settled, and the binding studies are negative. Separate groups reported that the tripeptide did not compete for binding at melanocortin receptors on mouse melanoma cells, and did not compete on macrophage-like cells even at millimolar concentrations. One study found that in Chinese hamster ovary cells engineered to carry the melanocortin-1 receptor, KPV raised intracellular calcium. Another found that in mice expressing a nonfunctional melanocortin-1 receptor, KPV treatment rescued every treated animal from death during colitis, and concluded its effects seem to be at least partly independent of that receptor. A later review states that KPV lacks the sequence motif required for binding to any known melanocortin receptor.
Compare KPV
A side-by-side page that tells KPV apart from another compound: how the two relate, which molecule the published evidence used, and whether they have been compared directly.
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Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.