
Melanotan 2 Research: The Melanocortin System, Structure and Preclinical Findings
A receptor-biology look at Melanotan 2 research: peptide structure, melanocortin receptor agonism, and preclinical findings on the MC1R, MC3R, MC4R, and MC5R subtypes.
Melanocortin receptor agonists and endocrine signaling peptides for receptor binding and hormonal pathway research.
Melanocortin peptides act on five POMC-derived G-protein-coupled receptors (MC1R–MC5R) across diverse tissues. PT-141 is a cyclic melanocortin agonist studied for its central effects on hypothalamic arousal circuits. Kisspeptin is the master regulator of the hypothalamic-pituitary-gonadal axis, investigated for puberty onset and reproductive function. Oxytocin is a nonapeptide studied for social bonding and stress modulation. VIP is a 28-amino-acid neuropeptide with vasodilatory, immunomodulatory, and neuroprotective properties.

A receptor-biology look at Melanotan 2 research: peptide structure, melanocortin receptor agonism, and preclinical findings on the MC1R, MC3R, MC4R, and MC5R subtypes.
For in-vitro research use only. Not for human or veterinary use.