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Research Use Only · Not for human or veterinary consumption.
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Safety Data Sheet
In the 16-section GHS format covering identification, hazards, handling, storage and disposal.
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What is AICAR?
AICAR is a nucleoside, not a peptide. It is a sugar joined to a nitrogen-containing ring. The phosphate form it is converted into inside cells occurs naturally as an intermediate in the pathway cells use to build purines, the components of DNA and RNA, and under the name acadesine it has been studied as a drug since the 1990s. Once inside a cell it is converted into a phosphate-carrying form called ZMP, which resembles AMP closely enough to switch on AMP-activated protein kinase, or AMPK, the enzyme that responds when a cell's energy runs low. Research on it covers energy metabolism in muscle and liver, endurance in mice, and the ways it acts on cells with and without AMPK.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
AICAR Research & Reference
What AICAR does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Frequently Asked Questions
Is AICAR third-party tested for purity?+−
Yes. Every batch of AICAR is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
What does "Research Use Only" mean?+−
It means AICAR is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals.
How is AICAR shipped and stored?+−
AICAR ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
Metabolic & Cellular Research
Related Compounds
From the blog
Background and context on this compound.
Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.