- Purity
- >99%
- Dispatch
- Dispatched next business day with cold-chain delivery
- Cold chain
- Temperature-controlled packaging from lab to door
- Certificate
- Batch-specific Certificate of Analysis available on this page
Multi-vial Discount Available
Select Size
Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
Quality Guaranteed
Every batch is HPLC-tested to >99% purity. Certificate of Analysis available on this page; MSDS available on request.
Verify Batch
Lot-level COA, Batch DF/MOT/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.
What is MOTS-c?
MOTS-c is a peptide of 16 amino acids. What makes it unusual is where its instructions are kept. Almost every protein in the body is coded in the DNA of the cell nucleus. This one is coded inside mitochondria, which carry a small genome of their own. It sits in a stretch of that genome once read only as part of a ribosomal RNA gene. Humanin, sold separately here, comes from a different stretch of the same genome and is a different peptide.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
MOTS-c Research & Reference
What MOTS-c does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Certificates of Analysis
Every batch is tested by an independent laboratory before release. The certificate covering this batch of MOTS-c, and its safety data sheet, are below as PDFs, so the figures on this page can be checked against the source.
Frequently Asked Questions
Is MOTS-c independently tested for purity?+−
Yes. Every batch of MOTS-c is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
Can I see the Certificate of Analysis before buying?+−
Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.
What does "Research Use Only" mean?+−
It means MOTS-c is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. MOTS-c is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. MOTS-c is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is MOTS-c shipped and stored?+−
MOTS-c ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
How is MOTS-c different from Humanin?+−
Both are mitochondrial-derived peptides, encoded by short reading frames inside mitochondrial DNA rather than the nuclear genome, but they come from different reading frames and are different molecules with different sequences. Humanin is sold separately on this site. Where a cited study measured both in the same experiment, they did not behave the same way; one paper found humanin rose significantly after acute endurance exercise while MOTS-c showed only a trend. No result reported for one peptide is presented as a result for the other anywhere on this page.
Has MOTS-c been given to people?+−
Not in any published study cited on this page. The four primary studies are mouse and cell work, or measurements of the peptide the body already makes under an exercise stimulus. Nobody in any of them received MOTS-c itself. The Published Research tab states this directly, and cites the studies so the claim can be checked rather than taken on trust.
From the blog
Background and context on this compound.
Related Compounds
>99%
>99%
>99%
>99%
>99%
>99%
>99%
>99%