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Research Use Only · Not for human or veterinary consumption.
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Certificates of Analysis
Every batch is tested by an independent laboratory before release.
Verify Batch. Lot-level COA, Batch DF/MOT/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.
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What is MOTS-c?
MOTS-c is a peptide of 16 amino acids. What makes it unusual is where its instructions are kept. Almost every protein in the body is coded in the DNA of the cell nucleus. This one is coded inside mitochondria, which carry a small genome of their own. It sits in a stretch of that genome once read only as part of a ribosomal RNA gene. Humanin, sold separately here, comes from a different stretch of the same genome and is a different peptide.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
MOTS-c Research & Reference
What MOTS-c does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
MOTS-c Batch Results
Batch DF/MOT/062026
- Laboratory
- Kovera Labs
- Certified
- August 13, 2026
- Sample
- 10 mg vial
- Report
- KVR-2026-C69D86
An independent laboratory, Kovera Labs, tested a sample from this batch. These are the results on its certificate.
Purity
Pass99.582%
RP-HPLC, C18 column, 214 nm
Identity
PassConfirmed
LC-MS
Purity is an HPLC figure: the main peak’s share of everything the detector recorded at one wavelength. It’s not a weight. What a purity figure counts →
Check it with the lab. Kovera Labs’ verification page looks a certificate up by its report number. Product, batch, date and results should match this page.
Chromatogram
RP-HPLC · C18 · DAD 214 nm
Frequently Asked Questions
Is MOTS-c third-party tested for purity?+−
Yes. Every batch of MOTS-c is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
Can I see the Certificate of Analysis before buying?+−
Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.
What does "Research Use Only" mean?+−
It means MOTS-c is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. MOTS-c is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. MOTS-c is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is MOTS-c shipped and stored?+−
MOTS-c ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
How is MOTS-c different from Humanin?+−
Both are mitochondrial-derived peptides, encoded by short reading frames inside mitochondrial DNA rather than the nuclear genome, but they come from different reading frames and are different molecules with different sequences. Humanin is sold separately on this site. Where a cited study measured both in the same experiment, they did not behave the same way; one paper found humanin rose significantly after acute endurance exercise while MOTS-c showed only a trend. No result reported for one peptide is presented as a result for the other anywhere on this page.
Has MOTS-c been given to people?+−
Not in any published study cited in the MOTS-c research article. Its primary studies are mouse and cell work, or measurements of the peptide the body already makes. Nobody in any of them received MOTS-c itself. That article states this directly, and cites the studies so the claim can be checked rather than taken on trust.
Compare MOTS-c
Side-by-side pages that tell MOTS-c apart from other compounds: how the two relate, which molecule the published evidence used, and whether they have been compared directly.
Metabolic & Cellular Research
Related Compounds
From the blog
Background and context on this compound.
Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.