Multi-vial Discount Available
Get notified when this batch is released
Enter your email and we'll let you know as soon as this product is available again.
Research Use Only · Not for human or veterinary consumption.
People also purchased
5mg · $43.00
5mg · $29.00
10mg · $43.00
Safety Data Sheet
In the 16-section GHS format covering identification, hazards, handling, storage and disposal.
- Next batch coming soon
- Quality Guaranteed
- Cold-Chain Shipping
- Free US Shipping Over $150
What is GDF-8 (Myostatin)?
GDF-8 is better known as myostatin. It is a protein the body makes to limit how much skeletal muscle it builds. It is the brake, not the accelerator. Two other products sold here, ACE-031 and Follistatin 344, work by getting in its way. A page that blurs the three ends up saying the opposite of what this one does. The active material is two identical protein chains of 109 residues, held together by a sulfur bridge. That is why the stated mass of about 25,000 describes the pair, not one chain.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
GDF-8 (Myostatin) Research & Reference
What GDF-8 (Myostatin) does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Frequently Asked Questions
Is GDF-8 (Myostatin) third-party tested for purity?+−
Yes. Every batch of GDF-8 (Myostatin) is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
What does "Research Use Only" mean?+−
It means GDF-8 (Myostatin) is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. GDF-8 is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. GDF-8 is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is GDF-8 (Myostatin) shipped and stored?+−
GDF-8 (Myostatin) ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
Does GDF-8 increase muscle mass?+−
No. GDF-8, also called myostatin, is a negative regulator of skeletal muscle mass; its role in published work is to limit muscle growth. Mice and cattle carrying disrupting mutations in the gene have markedly more muscle than animals with a working copy. The compounds that raise muscle mass in that literature are the ones that block this molecule, and they are different products.
What is the difference between GDF-8, ACE-031 and Follistatin 344?+−
GDF-8 is the ligand. ACE-031 is a soluble decoy receptor built from the activin receptor type IIB, which traps it. Follistatin 344 is a binding protein that also binds it. One 2001 study reported all three relationships in the same paper: the purified GDF-8 dimer bound the activin type IIB receptor, and follistatin blocked that binding. The three are sold separately here and results reported for one are not reported for another.
What does the molecular weight refer to?+−
The mature protein is a disulfide-linked homodimer of two identical 109-residue chains. The approximate mass of 25,000 g/mol describes that pair. A single chain is roughly half of it.
Metabolic & Cellular Research
Related Compounds
From the blog
Background and context on this compound.
Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.