Cognitive & Neuropeptide Research

Humanin Research Peptide

Humanin is a chain of 24 amino acids.

Humanin research peptide, >99% purity by HPLC, CAS 330936-69-1, lyophilized powder for in-vitro laboratory research, Pure Peptides
Purity
>99%
Dispatch
Dispatched next business day with cold-chain delivery
Cold chain
Temperature-controlled packaging from lab to door
Certificate
Batch-specific Certificate of Analysis available on this page
$65.00

Multi-vial Discount Available

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Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.

Quality Guaranteed

Every batch is HPLC-tested to >99% purity. Certificate of Analysis available on this page; MSDS available on request.

Verify Batch

Lot-level COA, Batch DF/HUM/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.

What is Humanin?

Humanin is a chain of 24 amino acids. It is unusual in where it comes from: the instructions for making it sit inside the DNA of the mitochondria, the small compartments that supply a cell with energy, in a stretch that was not thought to code for anything. It was found in 1998 by screening a gene library made from a brain region affected by protein aggregation. Most of the published work is in cells rather than animals. Colivelin, sold separately here, contains a modified piece of this chain joined to a second one, and is a different substance.

Technical Specs

CAS Number330936-69-1
Molecular FormulaC119H204N34O32S2
Molecular Weight2,687.28 g/mol
SequenceMAPRGFSCLLLLTSEIDLPVKRRA
Purity>99%
Physical FormLyophilized Powder
TestingHPLC + MS-UPLC
SKUHUM
Batch No.DF/HUM/062026

Labeled quantity is net peptide content, not gross salt weight.

Humanin Research & Reference

What Humanin does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.

Certificates of Analysis

Every batch is tested by an independent laboratory before release. The certificate covering this batch of Humanin, and its safety data sheet, are below as PDFs, so the figures on this page can be checked against the source.

Frequently Asked Questions

Is Humanin independently tested for purity?+

Yes. Every batch of Humanin is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.

Can I see the Certificate of Analysis before buying?+

Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.

What does "Research Use Only" mean?+

It means Humanin is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. Humanin is legal to purchase in the United States for in vitro and non-clinical laboratory research. It carries no FDA approval or therapeutic indication for human use. Humanin is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.

How is Humanin shipped and stored?+

Humanin ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.

Is this native humanin or an analogue?+

Native humanin, the 24-residue sequence MAPRGFSCLLLLTSEIDLPVKRRA. A large part of the published literature uses S14G-humanin, written HNG, or other analogues that are reported as more potent, and some papers describe an analogue without naming it. Where a finding on the Published Research tab comes from an analogue rather than from the native peptide, the tab says so.

Is Humanin the same as Colivelin?+

No. Colivelin, supplied separately, carries a humanin-derived sequence joined to a second sequence from a different protein, and the humanin portion is a modified variant rather than the native peptide. It is a distinct compound with its own literature. Findings for one are not findings for the other.

From the blog

Background and context on this compound.

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