Colivelin Research Peptide
Colivelin is a made-up chain, built by joining two shorter chains that came from different places.
Multi-vial Discount Available
Select Size
Research Use Only · Not for human or veterinary consumption.
People also purchased
5mg · $43.00
5mg · $29.00
10mg · $43.00
Safety Data Sheet
In the 16-section GHS format covering identification, hazards, handling, storage and disposal.
- Ships Next Day
- Quality Guaranteed
- Cold-Chain Shipping
- Free US Shipping Over $150
What is Colivelin?
Colivelin is a made-up chain, built by joining two shorter chains that came from different places. One end is a piece called ADNF, short for activity-dependent neurotrophic factor. The other is a shortened and altered version of humanin, a natural peptide whose instructions sit in the DNA of the mitochondria. That altered version is 17 links long where humanin itself is 24, and it carries changes at four positions, so it is not the same substance as the humanin sold separately here. Colivelin was built in a Japanese laboratory, and its originating paper reports it about a hundredfold more potent than its humanin-derived half and at least as potent as the other half.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
Colivelin Research & Reference
What Colivelin does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
Frequently Asked Questions
Is Colivelin third-party tested for purity?+−
Yes. Every batch of Colivelin is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
What does "Research Use Only" mean?+−
It means Colivelin is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. Colivelin is legal to purchase in the United States for in vitro and non-clinical laboratory research. It carries no FDA approval or therapeutic indication for human use. Colivelin is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is Colivelin shipped and stored?+−
Colivelin ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
Is Colivelin the same as Humanin?+−
No, and the relationship runs through a third molecule. Colivelin is activity-dependent neurotrophic factor fused to AGA-(C8R)HNG17, which is a 17-residue derivative of humanin carrying substitutions. Humanin itself, supplied separately, is the native 24-residue peptide. All three are distinct compounds, and a result for one is not a result for the others.
Is Colivelin more potent than its components?+−
In the study that built it, Colivelin suppressed cell death at 100 femtomolar while the humanin-derived component alone required 10 picomolar in the same experiment. In transgenic ALS model mice, Colivelin improved motor performance and prolonged survival; the same group had reported earlier that the ADNF component alone improved motor performance without significantly prolonging survival. The Colivelin research article gives both comparisons with their models.
Cognitive & Neuropeptide Research
Related Compounds
>99%
>99%
>99%
>99%
Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.