Colivelin Research Peptide
Colivelin is a made-up chain, built by joining two shorter chains that came from different places.
- Purity
- >99%
- Dispatch
- Dispatched next business day with cold-chain delivery
- Cold chain
- Temperature-controlled packaging from lab to door
- Certificate
- Certificate of Analysis available on request for this batch
Multi-vial Discount Available
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Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
Quality Guaranteed
Every batch is HPLC-tested to >99% purity. Certificate of Analysis available on request; MSDS available on request.
Certificate of Analysis Available on Request
Request this batch's certificate using your order number.
What is Colivelin?
Colivelin is a made-up chain, built by joining two shorter chains that came from different places. One end is a piece called ADNF, short for activity-dependent neurotrophic factor. The other is a shortened and altered version of humanin, a natural peptide whose instructions sit in the DNA of the mitochondria. That altered version is 17 links long where humanin itself is 24, and it carries changes at two positions, so it is not the same substance as the humanin sold separately here. Colivelin was built in a Japanese laboratory to be more potent than either half.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
Colivelin Research & Reference
What Colivelin does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Safety Data Sheet
The safety data sheet for Colivelin is below as a PDF, in the 16-section GHS format covering identification, hazards, handling, storage and disposal.
Frequently Asked Questions
Is Colivelin independently tested for purity?+−
Yes. Every batch of Colivelin is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
What does "Research Use Only" mean?+−
It means Colivelin is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. Colivelin is legal to purchase in the United States for in vitro and non-clinical laboratory research. It carries no FDA approval or therapeutic indication for human use. Colivelin is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is Colivelin shipped and stored?+−
Colivelin ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
Is Colivelin the same as Humanin?+−
No, and the relationship runs through a third molecule. Colivelin is activity-dependent neurotrophic factor fused to AGA-(C8R)HNG17, which is a 17-residue derivative of humanin carrying substitutions. Humanin itself, supplied separately, is the native 24-residue peptide. All three are distinct compounds, and a result for one is not a result for the others.
Is Colivelin more potent than its components?+−
In the study that built it, Colivelin suppressed cell death at 100 femtomolar while the humanin-derived component alone required 10 picomolar in the same experiment. In a separate mouse study, the ADNF component alone improved motor performance without significantly prolonging survival, while Colivelin did both. The Published Research tab gives both comparisons with their models.
Related Compounds
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