Buy PAL-GHK Research Peptide
Supplied as a lyophilized powder and independently verified to ≥98% purity by HPLC and MS-UPLC analysis.
Buy PAL-GHK Research Peptide
Supplied as a lyophilized powder and independently verified to ≥98% purity by HPLC and MS-UPLC analysis.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
Verify Batch
Lot-level COA, Batch DF/PAL/062026
What is PAL-GHK?
PAL-GHK is a skin-penetrating version of the natural copper peptide GHK, with a fatty-acid tail added to help it cross the skin barrier. It is studied in skin-cell research for its effects on collagen and the skin's support scaffold.
- A fatty-acid-tagged form of the GHK tripeptide for better skin penetration
- Studied in skin-cell research for its effects on collagen and elastin
- The fatty-acid tag helps it reach deeper skin layers
- Studied alongside copper-bound GHK-Cu in skin-cell research
For research use only. Not approved for human therapeutic use.
PAL-GHK (Palmitoyl Tripeptide-1) is a synthetic lipopeptide formed by conjugating palmitic acid to the copper-binding tripeptide GHK (Gly-His-Lys), typically supplied without the coordinated copper ion present in the parent GHK-Cu complex. GHK-Cu, first isolated from human plasma, has been shown in vitro to stimulate collagen synthesis in fibroblast cultures at low, physiologically relevant concentrations, consistent with GHK's proposed role as a wound-healing signal released during collagen breakdown [1]. The palmitoyl modification is intended to increase the hydrophobicity of the GHK sequence, and a 2024 review of GHK-based anti-wrinkle peptides reports that this raises PAL-GHK's calculated partition coefficient and its measured skin permeation relative to both unmodified GHK and GHK-Cu [2]. The same review is explicit that this permeability rationale, rather than dedicated bioactivity data, is the current basis for PAL-GHK's cosmetic use, noting that cellular or clinical studies evaluating its own anti-wrinkle activity are still lacking in the published literature [2].
References
Scientific Review
Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer
Reviewed for scientific accuracy, 14 June 2026
Lyophilised powder: store at -20 °C or below, away from light and moisture. Once reconstituted in an appropriate laboratory diluent (e.g. sterile water, PBS, or assay buffer), store at 2–8 °C and use within the validated period for your protocol. Do not refreeze.
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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis available on this page; MSDS available on request.