Melanocortin & Endocrine Research

Melanotan II Research Peptide

Melanotan II is a synthetic ring-shaped peptide, built from part of alpha-MSH.

$46.00

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Research Use Only · Not for human or veterinary consumption.

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Melanotan II research peptide, >99% purity by HPLC, CAS 121062-08-6, also known as MT-2, MT-II, lyophilized powder for in-vitro laboratory research, Pure Peptides
>99% purityHPLC + MS-UPLC

Certificates of Analysis

Every batch is tested by an independent laboratory before release.

Verify Batch. Lot-level COA, Batch PP/MT2/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.

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What is Melanotan II?

Melanotan II is a synthetic ring-shaped peptide, built from part of alpha-MSH. That is the hormone which tells pigment cells to make melanin. A chemical bridge between two side chains closes the ring. Holding the molecule in one shape, along with two swapped building blocks, makes it far more potent than the natural hormone in lab tests, and far longer-lasting. Bremelanotide, listed separately here, is a related molecule derived from it. Afamelanotide is a different analogue again.

Product information reviewed by Dr. Martina Rossi, PhD

Scientific Contributor and Reviewer · Reviewed

Melanotan II Research & Reference

What Melanotan II does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.

Technical Specs

CAS Number121062-08-6
Also Known AsMT-2, MT-II
Molecular FormulaC50H69N15O9
Molecular Weight1024.18 g/mol
SequenceAc-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-NH2
Purity>99%
Physical FormLyophilized Powder
TestingHPLC + MS-UPLC
SKUMT2
Batch No.PP/MT2/062026

Labeled quantity is net peptide content, not gross salt weight.

Melanotan II Batch Results

Batch PP/MT2/062026

Laboratory
Kovera Labs
Certified
August 13, 2026
Sample
10 mg vial
Report
KVR-2026-6FFEB5

An independent laboratory, Kovera Labs, tested a sample from this batch. These are the results on its certificate.

Purity

Pass

99.476%

RP-HPLC, C18 column, 214 nm

Identity

Pass

Confirmed

LC-MS

Purity is an HPLC figure: the main peak’s share of everything the detector recorded at one wavelength. It’s not a weight. What a purity figure counts →

Check it with the lab. Kovera Labs’ verification page looks a certificate up by its report number. Product, batch, date and results should match this page.

Chromatogram

RP-HPLC · C18 · DAD 214 nm

Chromatogram from certificate KVR-2026-6FFEB5 for Melanotan II batch PP/MT2/062026.
The detector trace printed on the certificate, from the run behind the purity figure. How to read this certificate →

Frequently Asked Questions

Is Melanotan II third-party tested for purity?+

Yes. Every batch of Melanotan II is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.

Can I see the Certificate of Analysis before buying?+

Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.

What does "Research Use Only" mean?+

It means Melanotan II is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. Melanotan II is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. Melanotan II is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.

How is Melanotan II shipped and stored?+

Melanotan II ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.

What does the published clinical literature on Melanotan II report?+

A substantial part of the indexed literature on this compound consists of case reports and clinical toxicology reports arising from unregulated use, rather than receptor pharmacology. Published reports describe melanoma in situ and changes in existing moles, including one case in which sequential video dermoscopy recorded changes that made a mole difficult to distinguish from a melanoma. Others describe severe muscle breakdown with intensive-care admission, and a prolonged painful erection that required surgery after standard first-line measures failed. Each is a single case. Case reports do not establish incidence and they do not establish causation, but they are what the literature contains.

What was found when products sold online were analyzed?+

One published study bought vials sold as injectable tanning products from three online shops and analyzed them by liquid chromatography and tandem mass spectrometry. Each shop claimed 10 mg of Melanotan II per vial. The measured content ranged from 4.32 to 8.84 mg. Samples from two of the three shops contained unidentified impurities of between 4.1 and 5.9 per cent. A separate study identified Melanotan II and bremelanotide in samples confiscated by police alongside anabolic steroids and stimulants.

Is this the same as bremelanotide?+

No. Bremelanotide is a further analogue derived from Melanotan II and is listed separately on this site. A separate alpha-MSH analogue again, afamelanotide, is a different molecule from both. No result reported for either is a result for this one.

Compare Melanotan II

A side-by-side page that tells Melanotan II apart from another compound: how the two relate, which molecule the published evidence used, and whether they have been compared directly.

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From the blog

Background and context on this compound.

Dr. Martina Rossi, PhD

Reviewed for scientific accuracy

Dr. Martina Rossi, PhD

PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer

Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.

Reviewed ORCIDGoogle ScholarTeam profile →

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