VIP (Vasoactive Intestinal Peptide) Research Peptide

Yes. Every batch of VIP (Vasoactive Intestinal Peptide) is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.

Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.

It means VIP (Vasoactive Intestinal Peptide) is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. VIP is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. No approved product containing this peptide was located. VIP is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.

VIP (Vasoactive Intestinal Peptide) ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.

They are two separate receptors, both bound by VIP and both bound by a second peptide called PACAP. The published findings on this page divide between them: the macrophage work acts through VPAC1, and the circadian work in the suprachiasmatic nucleus concerns VPAC2, encoded by the gene Vipr2. A study that built nine simplified VIP analogues achieved more than 2,000-fold selectivity for VPAC1 in one of them and no VPAC2 selectivity in any of them, which is a measure of how difficult the two are to separate pharmacologically.

No. PACAP is a different peptide that happens to bind the same two receptors, which is why a large part of the literature reports the two together. The immune study cited on the Published Research tab reports VIP and PACAP throughout and does not separate them in its results, so every sentence drawn from it on this page names both. Where a study used only one, the sentence says which.