VIP (Vasoactive Intestinal Peptide) Research Peptide
VIP is a peptide of 28 amino acids, first isolated from pig small intestine in 1970.
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Research Use Only · Not for human or veterinary consumption.
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Certificates of Analysis
Every batch is tested by an independent laboratory before release.
Verify Batch. Lot-level COA, Batch DF/VIP/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.
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What is VIP (Vasoactive Intestinal Peptide)?
VIP is a peptide of 28 amino acids, first isolated from pig small intestine in 1970. Its tail end carries an amide group, and it has no sulfur bridges. It binds two receptors with high affinity, VPAC1 and VPAC2, and a third, PAC1, weakly. Those are different proteins doing different jobs in different tissues. A second peptide, PACAP, binds VPAC1 and VPAC2 with high affinity as well, and is the high-affinity ligand at PAC1. That is why so much published work reports the pair together, and why every line below says which was used.
Product information reviewed by Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer · Reviewed
VIP (Vasoactive Intestinal Peptide) Research & Reference
What VIP (Vasoactive Intestinal Peptide) does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.
Technical Specs
Labeled quantity is net peptide content, not gross salt weight.
VIP (Vasoactive Intestinal Peptide) Batch Results
Batch DF/VIP/062026
- Laboratory
- Kovera Labs
- Certified
- August 13, 2026
- Sample
- 10 mg vial
- Report
- KVR-2026-D6E31D
An independent laboratory, Kovera Labs, tested a sample from this batch. These are the results on its certificate.
Purity
Pass99.702%
RP-HPLC, C18 column, 214 nm
Identity
PassConfirmed
LC-MS
Purity is an HPLC figure: the main peak’s share of everything the detector recorded at one wavelength. It’s not a weight. What a purity figure counts →
Check it with the lab. Kovera Labs’ verification page looks a certificate up by its report number. Product, batch, date and results should match this page.
Chromatogram
RP-HPLC · C18 · DAD 214 nm
Frequently Asked Questions
Is VIP (Vasoactive Intestinal Peptide) third-party tested for purity?+−
Yes. Every batch of VIP (Vasoactive Intestinal Peptide) is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.
Can I see the Certificate of Analysis before buying?+−
Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.
What does "Research Use Only" mean?+−
It means VIP (Vasoactive Intestinal Peptide) is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. VIP is legal to purchase in the United States for in vitro and non-clinical laboratory research. It has no FDA approval and no approved human use. No approved product containing this peptide was located. VIP is not a scheduled substance under the Controlled Substances Act. Sold strictly for qualified research use, not human or veterinary administration.
How is VIP (Vasoactive Intestinal Peptide) shipped and stored?+−
VIP (Vasoactive Intestinal Peptide) ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.
What is the difference between VPAC1 and VPAC2?+−
They are two separate receptors, both bound by VIP and both bound by a second peptide called PACAP. Published findings divide between them: anti-inflammatory work in mouse macrophages acts through VPAC1, and circadian work in the mouse suprachiasmatic nucleus concerns VPAC2, encoded by the gene Vipr2. A study that built nine simplified VIP analogues achieved more than 2,000-fold selectivity for VPAC1 in one of them and no VPAC2 selectivity in any of them. Other work has produced highly selective VPAC2 agonists from different peptide series.
Is research on PACAP research on VIP?+−
No. PACAP is a different peptide that happens to bind the same two receptors, which is why a large part of the literature reports the two together.
Melanocortin & Endocrine Research
Related Compounds
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>99%
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Reviewed for scientific accuracy
Dr. Martina Rossi, PhD
PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer
Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.