Growth Hormone Axis Research

IGF-1 LR3 Research Protein

IGF-1 LR3 is a laboratory-made version of IGF-1, a growth factor the body produces in response to growth hormone.

$87.00

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1vial

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Research Use Only · Not for human or veterinary consumption.

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IGF-1 LR3 research protein, >99% purity by HPLC, CAS 143045-27-6, lyophilized powder for in-vitro laboratory research, Pure Peptides
>99% purityHPLC + MS-UPLC

Certificates of Analysis

Every batch is tested by an independent laboratory before release.

Verify Batch. Lot-level COA, Batch PP/IGF/062026. Check the batch number printed on your vial against the certificate below, which reports the tests run on it.

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What is IGF-1 LR3?

IGF-1 LR3 is a laboratory-made version of IGF-1, a growth factor the body produces in response to growth hormone. Two things have been changed. One building block near the front has been swapped for arginine, and a 13-link tail has been added to the front end. Native IGF-1 is 70 links long; this version is 83. The swap makes it stick less to the carrier proteins that normally hold IGF-1 in check. The tail was added to make the protein easier to manufacture, and its developers found it also changes how those carrier proteins handle it.

Product information reviewed by Dr. Martina Rossi, PhD

Scientific Contributor and Reviewer · Reviewed

IGF-1 LR3 Research & Reference

What IGF-1 LR3 does in published studies, and how to work with it in the laboratory, are covered in full on two dedicated pages rather than summarised here, so neither the evidence nor the handling detail is cut short.

Technical Specs

CAS Number143045-27-6
Molecular FormulaC400H619N111O115S9
Molecular Weight9,111.45 g/mol
SequenceMFPAMPLSSLFVNGPRTLCGAELVDALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSA
Purity>99%
Physical FormLyophilized Powder
TestingHPLC + MS-UPLC
SKUIGF1LR3
Batch No.PP/IGF/062026

IGF-1 LR3 Batch Results

Batch PP/IGF/062026

Laboratory
Kovera Labs
Certified
August 6, 2026
Sample
1 mg vial
Report
KVR-2026-35412A

An independent laboratory, Kovera Labs, tested a sample from this batch. These are the results on its certificate.

Purity

Pass

99.602%

RP-HPLC, C18 column, 214 nm

Identity

Pass

Confirmed

LC-MS

Purity is an HPLC figure: the main peak’s share of everything the detector recorded at one wavelength. It’s not a weight. What a purity figure counts →

Check it with the lab. Kovera Labs’ verification page looks a certificate up by its report number. Product, batch, date and results should match this page.

Chromatogram

RP-HPLC · C18 · DAD 214 nm

Chromatogram from certificate KVR-2026-35412A for IGF-1 LR3 batch PP/IGF/062026.
The detector trace printed on the certificate, from the run behind the purity figure. How to read this certificate →

Frequently Asked Questions

Is IGF-1 LR3 third-party tested for purity?+

Yes. Every batch of IGF-1 LR3 is tested by an independent third-party laboratory using HPLC and MS-UPLC, confirming purity and mass identity before the batch is released. Pure Peptides does not test its own material.

Can I see the Certificate of Analysis before buying?+

Yes. The Certificate of Analysis for the batch currently in stock can be viewed and downloaded directly on this page, before you place an order. Each certificate states the batch number, the measured purity, and the date of analysis, and can be verified independently with the issuing laboratory using the report number it carries.

What does "Research Use Only" mean?+

It means IGF-1 LR3 is supplied for in-vitro laboratory research and for no other purpose, and must not be administered to humans or animals. IGF-1 LR3 is legal to purchase in the United States for in vitro and non-clinical laboratory research. It carries no FDA approval or therapeutic indication for human use. As an IGF-1 analogue, IGF-1 LR3 appears in section S2 of the WADA Prohibited List for competitive athletes, a separate consideration from its legal research status. Sold strictly for qualified research use, not human or veterinary administration.

How is IGF-1 LR3 shipped and stored?+

IGF-1 LR3 ships from US stock with cold-chain packaging and full tracking; orders placed before noon EST on business days are typically dispatched the same business day. On arrival, store the lyophilized powder at -20°C or below, dry and protected from light.

Does IGF-1 LR3 increase growth in animal studies?+

It depends on the species, and published work is explicit about that. Analogues of this type raise growth in rats. In pigs, a four-day infusion reduced average daily gain and food intake, lowered plasma IGFBP-3, IGF-I and insulin, and cut mean plasma growth hormone by 23%. Researchers should read the primary literature for the species they are working in.

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From the blog

Background and context on this compound.

Dr. Martina Rossi, PhD

Reviewed for scientific accuracy

Dr. Martina Rossi, PhD

PhD, Université Grenoble Alpes · Scientific Contributor and Reviewer

Dr. Rossi's doctoral research at Université Grenoble Alpes examined the vascular functions of bone morphogenetic proteins. Her peer-reviewed work spans cell and molecular biology, vascular biology, and gene therapy, in journals including Cardiovascular Research, Scientific Reports, and Brain Sciences. She reviews Pure Peptides' product, reference, and research pages for scientific accuracy against the sources they cite.

Reviewed ORCIDGoogle ScholarTeam profile →

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