Buy CJC-1295 (No DAC) Research Peptide
Supplied as a lyophilised powder and independently verified to ≥98% purity by HPLC and MS-UPLC analysis.
Buy CJC-1295 (No DAC) Research Peptide
Supplied as a lyophilised powder and independently verified to ≥98% purity by HPLC and MS-UPLC analysis.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA on Request
Every batch
Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA on Request
Every batch
Ships Next Day
Orders confirmed before 12pm EST ship the same business day; orders after 12pm EST ship the next business day. Monday to Friday.
What is CJC-1295 (No DAC)?
CJC-1295 is a synthetic version of GHRH (the hormone that tells the pituitary to release growth hormone), with changes that make it last longer than natural GHRH. It is used in animal and laboratory research to study growth-hormone release.
- A longer-lasting version of growth hormone-releasing hormone (GHRH), residues 1 to 29
- Used in research to study how the pituitary releases growth hormone
- Its longer action makes it a useful tool for studying sustained GHRH signaling
- Studied in animal research for its effects on the growth hormone and IGF-1 system
For research use only. Not approved for human therapeutic use.
CJC-1295 without DAC, also referred to as Modified GRF(1-29) or Mod GRF(1-29), is a synthetic 29-amino acid analogue of growth hormone-releasing hormone (GHRH). With the molecular formula C152H252N44O42 and a molecular weight of 3367.90 g/mol, CJC-1295 No DAC (CAS 863288-34-0) incorporates four amino acid substitutions at positions known to be vulnerable to enzymatic cleavage in native GHRH. Produced via solid-phase peptide synthesis, Modified GRF(1-29) acts at the GHRH receptor (GHRH-R).
CJC-1295 No DAC has been extensively investigated in preclinical neuroendocrine research as a stabilised GHRH analogue that retains a relatively short half-life compared to the DAC-conjugated variant. This pharmacokinetic profile has made Mod GRF(1-29) a key subject of preclinical interest in studies examining pulsatile GH release patterns, with its rapid-clearance kinetics characterised as consistent with episodic endogenous GHRH signalling dynamics. In vitro studies in rat anterior pituitary cell preparations have examined Modified GRF(1-29)’s binding characteristics and receptor activation kinetics at the GHRH-R, documenting adenylate cyclase stimulation and intracellular cAMP accumulation as primary readouts of GHRH-R engagement [1]. Rodent model studies have investigated CJC-1295 No DAC’s interaction with the somatotropic axis under both isolated and combination protocols, documenting GH secretion dynamics and the synergistic relationship between GHRH-R agonists and ghrelin-mimetic secretagogues such as GHRP-6 under controlled preclinical conditions [2].
CJC-1295 (No DAC) is produced to research-grade standards and independently verified by third-party HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
References
Scientific Review
Dr. Martina Rossi, PhD
Scientific Contributor and Reviewer
Reviewed for scientific accuracy, 14 June 2026
Lyophilised powder: store at -20 °C or below, away from light and moisture. Once reconstituted in an appropriate laboratory diluent (e.g. sterile water, PBS, or assay buffer), store at 2–8 °C and use within the validated period for your protocol. Do not refreeze.
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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and MSDS available on request.